<?xml version="1.0" encoding="utf-8"?><feed xmlns="http://www.w3.org/2005/Atom" ><generator uri="https://jekyllrb.com/" version="4.3.4">Jekyll</generator><link href="https://chem-bla-ics.linkedchemistry.info/feed/by_tag/postgenomic.xml" rel="self" type="application/atom+xml" /><link href="https://chem-bla-ics.linkedchemistry.info/" rel="alternate" type="text/html" /><updated>2026-07-18T13:36:15+00:00</updated><id>https://chem-bla-ics.linkedchemistry.info/feed/by_tag/postgenomic.xml</id><title type="html">chem-bla-ics</title><subtitle>Chemblaics (pronounced chem-bla-ics) is the science that uses open science and computers to solve problems in chemistry, biochemistry and related fields.</subtitle><author><name>Egon Willighagen</name></author><entry><title type="html">Scintilla and Postgenomic.com on Linux 2.6.17+</title><link href="https://chem-bla-ics.linkedchemistry.info/2007/11/12/scintilla-and-postgenomiccom-on-linux.html" rel="alternate" type="text/html" title="Scintilla and Postgenomic.com on Linux 2.6.17+" /><published>2007-11-12T00:00:00+00:00</published><updated>2007-11-12T00:00:00+00:00</updated><id>https://chem-bla-ics.linkedchemistry.info/2007/11/12/scintilla-and-postgenomiccom-on-linux</id><content type="html" xml:base="https://chem-bla-ics.linkedchemistry.info/2007/11/12/scintilla-and-postgenomiccom-on-linux.html"><![CDATA[<p>That’s why blogging works! I reported last Friday on <a href="https://chem-bla-ics.linkedchemistry.info/2007/11/09/using-nintendo-wii-for-serious-science.html">using my Wii for reading <i class="fa-solid fa-recycle fa-xs"></i></a>
<a href="http://scintilla.nature.com/">Scintilla</a> and <a href="http://www.postgenomic.com/">Postgenomic.com</a>.
<a href="http://chem-bla-ics.blogspot.com/2007/11/using-nintendo-wii-for-serious-science.html#c9163469498026561308">Alf replied</a>: <!-- keep link --></p>

<blockquote>
  <p>It is the Linux kernel, yes: TCP window scaling was switched on by default in kernels since about a year ago
(and in Vista too, I think), and one of our routers or firewalls doesn’t like it. We’re trying to get them
upgraded, but it takes a while…</p>
</blockquote>

<p>Ah, the trick word: TCP windows scaling. A quick google turned up a <a href="http://inodes.org/blog/2006/09/06/tcp-window-scaling-and-kernel-2617/">workaround in John’s Tidbits blog</a>:</p>

<blockquote>
  <p>There are 2 quick fixes. First you can simply turn off windows scaling all together by doing</p>

  <p>echo 0 &gt; /proc/sys/net/ipv4/tcp_window_scaling</p>

  <p>but that limits your window to 64k. Or you can limit the size of your TCP buffers back to pre 2.6.17 kernel values which means a wscale value of about 2 is used which is acceptable to most broken routers.</p>

  <p>echo “4096 16384 131072” &gt; /proc/sys/net/ipv4/tcp_wmem
echo “4096 87380 174760” &gt; /proc/sys/net/ipv4/tcp_rmem</p>

  <p>The original values would have had 4MB in the last column above which is what was allowing these massive windows.</p>

  <p>In a thread somewhere which I can’t find anymore Dave Miller had a great quote along the lines of</p>

  <p>“I refuse to workaround it, window scaling has been part of the protocol since 1999, deal with it.”</p>
</blockquote>

<p>That worked for me. I think Dave Miller is right, but can’t resist reading Scintilla and Postgenomic.com on my desktop too ;)</p>]]></content><author><name>Egon Willighagen</name></author><category term="linux" /><category term="postgenomic" /><summary type="html"><![CDATA[That’s why blogging works! I reported last Friday on using my Wii for reading Scintilla and Postgenomic.com. Alf replied:]]></summary></entry><entry><title type="html">Using the Nintendo Wii for serious science…</title><link href="https://chem-bla-ics.linkedchemistry.info/2007/11/09/using-nintendo-wii-for-serious-science.html" rel="alternate" type="text/html" title="Using the Nintendo Wii for serious science…" /><published>2007-11-09T00:00:00+00:00</published><updated>2007-11-09T00:00:00+00:00</updated><id>https://chem-bla-ics.linkedchemistry.info/2007/11/09/using-nintendo-wii-for-serious-science</id><content type="html" xml:base="https://chem-bla-ics.linkedchemistry.info/2007/11/09/using-nintendo-wii-for-serious-science.html"><![CDATA[<p>On my desktop, the <a href="http://scintilla.nature.com/">Scintilla</a> and <a href="http://postgenomic.com/">Postgenomic.com</a> websites
do not work. It is not a browser problem, but has something to do with TCP/IP packages not reaching its destination:
the browser. Euan told me they are aware of the problem, but apparently have not found a solution yet.</p>

<p>However, my <a href="http://wii.nintendo.com/">Wii</a> does not have the problem, which makes me wonder if it is a disagreement
between the <a href="http://www.nature.com/">Nature</a> server and my <a href="http://packages.ubuntu.com/gutsy/metapackages/linux">Linux kernel</a>…
Anyway, this is what the two website look like (first Scintilla, then Postgenomic.com):</p>

<p><img src="/assets/images/dsci0190.jpg" alt="" /></p>

<p><img src="/assets/images/dsci0191.jpg" alt="" /></p>

<p>(BTW, that was one <a href="https://doi.org/10.59350/v4pc6-9v569">very nice piece of work by Rich <i class="fa-solid fa-recycle fa-xs"></i></a>!
Make sure to also read the <a href="https://doi.org/10.59350/vhefz-rc472">follow up <i class="fa-solid fa-recycle fa-xs"></i></a>).</p>

<p>The only real disadvantage is that it does not integrate well with the things I do daily. If I see some interesting
post, and would like to tag it on <a href="http://del.icio.us/egonw">my del.icio.us account</a>, I have to google for it on
my desktop :(</p>

<p>(You thought I was going to talk about <a href="http://folding.stanford.edu/">F@H</a> or so, didn’t you? :)</p>]]></content><author><name>Egon Willighagen</name></author><category term="nintendo" /><category term="linux" /><category term="postgenomic" /><category term="justdoi:10.59350/v4pc6-9v569" /><category term="justdoi:10.59350/vhefz-rc472" /><summary type="html"><![CDATA[On my desktop, the Scintilla and Postgenomic.com websites do not work. It is not a browser problem, but has something to do with TCP/IP packages not reaching its destination: the browser. Euan told me they are aware of the problem, but apparently have not found a solution yet.]]></summary><media:thumbnail xmlns:media="http://search.yahoo.com/mrss/" url="https://chem-bla-ics.linkedchemistry.info/assets/images/dsci0190.jpg" /><media:content medium="image" url="https://chem-bla-ics.linkedchemistry.info/assets/images/dsci0190.jpg" xmlns:media="http://search.yahoo.com/mrss/" /></entry><entry><title type="html">Postgenomic.com maps upcoming conferences</title><link href="https://chem-bla-ics.linkedchemistry.info/2006/04/14/postgenomiccom-maps-upcoming.html" rel="alternate" type="text/html" title="Postgenomic.com maps upcoming conferences" /><published>2006-04-14T00:00:00+00:00</published><updated>2006-04-14T00:00:00+00:00</updated><id>https://chem-bla-ics.linkedchemistry.info/2006/04/14/postgenomiccom-maps-upcoming</id><content type="html" xml:base="https://chem-bla-ics.linkedchemistry.info/2006/04/14/postgenomiccom-maps-upcoming.html"><![CDATA[<p>Conference season is nearing. And just in time, <a href="http://web.archive.org/web/20240601063018mp_/http://postgenomic.com/">Postgenomic.com <i class="fa-solid fa-box-archive fa-xs"></i></a> added
a <a href="https://web.archive.org/web/20060513202812/http://postgenomic.com/meetings.php">conferences map <i class="fa-solid fa-box-archive fa-xs"></i></a> showing locations of upcoming and
recently finished conferences. Oh boy, do I want to set this up for chemoinformatics too!</p>

<p>Postgenomic.com makes use of the <a href="https://web.archive.org/web/20060813150816/http://postgenomic.com/about_reviews.php">rel=”conference” attribute <i class="fa-solid fa-box-archive fa-xs"></i></a> for the
<code class="language-plaintext highlighter-rouge">&lt;a&gt;</code> element. I’m not sure how they distinguish between upcoming and finished conferences (will need to check the
<a href="http://web.archive.org/web/20060519215119/http://www.postgenomic.org/">source code <i class="fa-solid fa-box-archive fa-xs"></i></a>). But I think some manual
processing is done, for example, to extract conference details, like title, location and dates. I assume the URL is used as unique identifier. Additionally,
the conferences are not ‘tagged’ yet, which should be possible too, as Postgenomic.com already associates tags from blog items with articles mentioned in
that item. But this is likely a temporary ommision.</p>

<p>I already saw <a href="https://web.archive.org/web/20060621192118/http://www.ched-ccce.org/confchem/">ChemConf2006 <i class="fa-solid fa-box-archive fa-xs"></i></a>
<a href="https://web.archive.org/web/20060513202812/http://postgenomic.com/meetings.php#conference_id_6">picked up <i class="fa-solid fa-box-archive fa-xs"></i></a> from an
<a href="https://chem-bla-ics.linkedchemistry.info/2006/04/02/free-online-chemconf-2006-conference.html">earlier post <i class="fa-solid fa-recycle fa-xs"></i></a> by me. Unfortunately, because it is an online conference, it does not show up on tha map :( The following two conference do have a physical location, and I hope the will appear on the map. If you wonder why I mention only these two, they are the two I will attend in the next 8 weeks, and will have presence of open source bio- and chemoinformatics software developers (at least one, me).</p>

<ul>
  <li><a href="https://gw1-prod.nbic.nl/http://cms1-prod-inside.nbic.nl/home/events/20060424_NBICevent">Netherlands Bioinformatics Conference <i class="fa-solid fa-link-slash fa-xs"></i></a>, April 24, Ede, The Netherlands</li>
  <li><a href="http://web.archive.org/web/20060612215907/http://infochim.u-strasbg.fr/recherche/europeen_chemistry/index.php">Workshop Chemoinformatics in Europe: Research and Teaching <i class="fa-solid fa-box-archive fa-xs"></i></a>, 29 May - 1 June, Obernai, France</li>
</ul>]]></content><author><name>Egon Willighagen</name></author><category term="postgenomic" /><category term="cheminf" /><summary type="html"><![CDATA[Conference season is nearing. And just in time, Postgenomic.com added a conferences map showing locations of upcoming and recently finished conferences. Oh boy, do I want to set this up for chemoinformatics too!]]></summary></entry></feed>