{
  "version": "https://jsonfeed.org/version/1.1",
  "title": "chem-bla-ics",
  "description": "Chemblaics (pronounced chem-bla-ics) is the science that uses open science and computers to solve problems in chemistry, biochemistry and related fields.",
  "home_page_url": "https://chem-bla-ics.linkedchemistry.info/",
  "feed_url": "https://chem-bla-ics.linkedchemistry.info/2008/05/08/re-what-should-nature-chemistry-paper.json",
  "icon": "https://chem-bla-ics.linkedchemistry.info/assets/images/chem-bla-ics_logo.png",
  "language": "en",
  "authors": [
    {
      "name": "Egon Willighagen",
      "url": "https://orcid.org/0000-0001-7542-0286",
      "_orcid": "0000-0001-7542-0286"
    }
  ],
  "items": [

    {
      "id": "https://doi.org/10.59350/g89pc-kz779",
      "url": "https://chem-bla-ics.linkedchemistry.info/2008/05/08/re-what-should-nature-chemistry-paper.html",
      "title": "Re: What should a Nature Chemistry paper look like?",
      "content_html": "<p><a href=\"http://blogs.nature.com/thescepticalchymist/author/neil_withers/\">Neil</a> <a href=\"http://blogs.nature.com/thescepticalchymist/2008/05/jj_day_98_service_with_a_simpl.html\">wondered</a>\n<em>“what a <a href=\"http://www.nature.com/nchem/\">Nature Chemistry</a> paper should look like”</em>, and asked the following questions.\nBelow are my answers.</p>\n\n<p><strong>1. HTML vs PDF: does anyone read the HTML articles? Do you read the PDF on-screen or print it out?</strong> <br />\nI typically read the HTML to scan if a paper is interesting for me. But because electronic paper is still too\nexpensive, I typically make a print of the PDF. I would love to print the HTML instead, if only it was not clouded\nwith advertisement, link menu’s etc. Many websites have a ‘Print View’ with just the content. Nicely layed out,\nbut without the menus/etc. NC should adopt this feature (or did I miss that option?).</p>\n\n<p><strong>2. Big vs little graphics: what does everyone else think about the tiny size of the graphics in ACS html articles?</strong> <br />\nI hate the small figures, because they make scanning the HTML more difficult.</p>\n\n<p><strong>3a. Tagging/’semantic web’: what do you think about the toys on the RSC’s Project Prospect?</strong> <br />\nI love tagging and semantic work up. Just browse my blog. I blogged a bit about <a href=\"http://chem-bla-ics.blogspot.com/search?q=project+prospect\">Project Prospect</a> <!-- keep link -->\nin the past, and also about using <a href=\"http://chem-bla-ics.blogspot.com/search?q=RDFa\">RDFa for semantic markup of chemistry</a>.  <!-- keep link -->\nI must also mention the nice semantic work by the <a href=\"http://www.beilstein-journals.org/\">Beilstein Journal</a>. Check the HTML\nsource for all the semantics and the link to the papers RDF version. I discussed some of that work\n<a href=\"https://chem-bla-ics.linkedchemistry.info/2008/04/22/quality-publishing-endnote-versus.html\">earlier <i class=\"fa-solid fa-recycle fa-xs\"></i></a>.</p>\n\n<p><strong>3b. What kind of things would you like to see tagged/linked to other content in Nature Chemistry?</strong> <br />\nI’d really like to see that Nature would pick up social tagging. For example, <a href=\"http://blogs.nature.com/wp/nascent/\">Euan/Ian/etc</a>\ncan tell you now tags from blogs/etc, can be used to find relevant other literature. Show\n<a href=\"http://www.connotea.org/\">Connotea</a> tags for NC papers on the NC website. Show related literature based on tag matching.\nI also recommend taking advantage of <a href=\"http://www.postgenomic.com/\">Postgenomic.com</a> and <a href=\"http://cb.openmolecules.net/\">Chemical blogspace</a>\nto complement papers with user comments, or at least link to them (just like linking to <a href=\"http://www.f1000biology.com/browse/\">F1000</a>).\nRegarding domain knowledge: link to whatever open database present, and encourage authors to provide links to public databases,\ne.g. by providing InChIs for molecules the describe, PDB identifiers, etc, etc.</p>\n\n<p><strong>4. 3D molecular structures: do these help your understanding of a paper?</strong> <br />\nAbsolutely! Henry Rzepa and Christopher Braddock recently showed how one can take advantage of\n<a href=\"http://www.jmol.org/\">Jmol</a> to explain what is going on (doi:<a href=\"https://doi.org/10.1021/np0705918\">10.1021/np0705918</a>),\nbut the ACS forgot to make it part of the main text :) A brilliant recent use of Jmol in explaining chemistry, is\n<a href=\"http://proteopedia.org/wiki/index.php/Main_Page\">ProtopediA</a> that uses <em>Jmol scripts</em> to visualize statements\nin the textual description in the wiki.</p>\n\n<p><strong>5. How useful to you are InChIs and SMILES?</strong> <br />\nWhile there is an <a href=\"http://opensmiles.org/\">OpenSMILES</a> project (part of the <a href=\"http://www.blueobelisk.org/\">Blue Obelisk movement</a>)\nto standardize SMILES, I’d go for InChI, and InChIKey if you mind the length of the InChI itself.</p>\n\n<p><strong>6. Forward linking: do you use it? Would you use an RSS feed that alerted you to new citations of a particular paper.</strong> <br />\nI am not sure what forward linking is, so cannot comment on that. However, I would use RSS feeds to alert me of new citations of\na particular paper. Right now, I am relying on <a href=\"http://scientific.thomson.com/products/wos/\">Web-of-Science</a> to do this for me,\nbut RSS are an excellent alternative. BTW, I was not aware of such feeds yet, and could use some advertisement!</p>\n\n<p><strong>7. Would you actually comment on papers if there was a comments box at the end?</strong> <br />\nNo, I would rather comment in my blog instead. That would place the comments in some perspective. See also my comment\non question 3b.</p>\n\n<p><strong>8. We really like the <a href=\"http://www.biochemj.org/bj/ev/381/0329/bj3810329_ev.htm\">Biochemical Society’s HTML article style</a> – do you?</strong> <br />\nNo, please do not inherit that layout. The use of frames should be discouraged anyway. It seems to be used to easily add\ninteractivity, but I am positive that Ajax/etc can be used to do all this inline.</p>\n\n<h4>References</h4>\n<div class=\"csl-bib-body\">\n    <div class=\"csl-entry\">Braddock, D. C., &#38; Rzepa, H. S. (2008). Structural Reassignment of Obtusallenes V, VI, and VII by GIAO-Based Density Functional Prediction. <i>Journal of Natural Products</i>, <i>71</i>(4), 728–730. https://doi.org/10.1021/np0705918 <a href=\"https://doi.org/10.1021/np0705918\">CrossRef</a> <a href=\"https://qlever.scholia.wiki/doi/10.1021/np0705918\">Scholia</a></div>\n  </div>",
      "summary": "Neil wondered “what a Nature Chemistry paper should look like”, and asked the following questions. Below are my answers.",
      
      "date_published": "2008-05-08T00:00:00+00:00",
      "date_modified": "2025-10-11T00:00:00+00:00",
      "tags": ["publishing","chemistry","inchi","rdfa"],
      "_references": [
        
          
          
            { "url": "https://doi.org/10.1021/np0705918", "doi": "10.1021/np0705918"
             }
            
          
        ],
      
      
      
      
      
      
        "authors": [ { "name": "Egon Willighagen", "url": "https://orcid.org/0000-0001-7542-0286" } ]
      
    }

  ]
}
